A covert CIA mind control program conducted from 1953 for over two decades, involving inhumane experiments including LSD administration and sensory deprivation.

Project MK-Ultra was a top-secret CIA mind control research program initiated in 1953. Motivated by fears that the Soviet Union and China were developing brainwashing techniques during the Cold War, the program was authorized by CIA Director Allen Dulles. It was overseen by Sidney Gottlieb of the CIA's Technical Services Staff and involved over 149 sub-projects across more than 80 institutions, including universities, hospitals, and prisons.
In 1973, amid the Watergate scandal, CIA Director Richard Helms ordered the mass destruction of related documents. However, approximately 20,000 pages were discovered through a Freedom of Information Act request in 1977, and the Senate Church Committee hearings subsequently exposed the program's full scope.
Experiments administering LSD without subjects' consent were conducted extensively. In Operation Midnight Climax, CIA operatives set up fake brothels in San Francisco where clients were secretly dosed with LSD and their reactions observed through one-way mirrors.
Army biological weapons researcher Frank Olson fell to his death from a hotel window days after being dosed with LSD without his consent. In 1975, the CIA admitted to the LSD dosing, and the family received an apology and compensation. A 2012 forensic re-examination raised the possibility of homicide.
At the Allan Memorial Institute at McGill University in Montreal, psychiatrist Donald Ewen Cameron conducted experiments called "psychic driving." Patients were subjected to massive electroshock therapy, drug cocktails, and prolonged forced sleep, resulting in severe lasting damage.